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Exendin-4 shares approximately 53% structural similarity with human GLP-1 but is resistant to DPP-4 enzyme degradation, giving it a significantly longer half-life than native human GLP-1, which breaks down in approximately 2 minutes

In other words, those prescribed semaglutide were more than seven times as likely to have NAION event compared to those on other medications

Most patients restart after 710 days of symptom improvement without any setback in their results

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